I regularly fire up the same applications: TextMate, a browser or two, mail programs, iTunes, a shell, irb and others. Now, while Quicksilver is excellent for firing up applications (and a lot of other things), I’d still be busy typing and/or mouse-pointing and clicking. And doing that is boring, cumbersome and not what I like to do anyway. I shouldn’t (have to) do it. And, in fact, I don’t. A little bit of Ruby code will do it:
#!/usr/bin/ruby
%w( <full_application_paths_go_here> ).each{ | app | system "open #{app} &" }
Replace <full_application_paths_go_here> with a list of space-delimited full application paths, save it into a file (in ~/bin presumably), make it executable and there you go. Actually, the language doesn’t matter at all here. The only thing that does matter is to fire up the applications.
Starting all most used applications is now just a few key strokes away. There’s certainly a very similar way to do this on other *nix OSes and Windows.